Argireline Solution 10%
A lightweight peptide serum designed to improve the look of expression lines in areas prone to deep-set folds.
A very targeted serum for people focused on expression lines in specific areas rather than broad all-over anti-aging.
Argireline at 10% is a clinical concentration — most peptide products containing this ingredient include it at a fraction of this level. The Ordinary naming it exactly and delivering it at this concentration is on-brand and gives users clear value vs. the guesswork in most "peptide" products.
After cleansing, before moisturizer — morning and evening. Apply to specific target areas (forehead, 11s, eye corners, smile lines) rather than the whole face.
People who want targeted line-specific peptide treatment alongside a broader multi-peptide serum. Anyone interested in the SNARE-inhibiting peptide mechanism without committing to a full Botox budget.
If used expecting immediate visible lifting like a cosmetic filler. Argireline works by reducing expression-line formation over time — it's a gradual, preventative mechanism. Patience and consistency determine results.
Peptide serums are among the gentlest actives — Argireline is particularly non-irritating. Fine to continue during a barrier flare-up. If simplifying, you can pause it without concern, but it's not a likely contributor to irritation.
- A multi-peptide broad-spectrum serum on the rest of the face while this targets expression zones specifically
- A ceramide moisturizer on top
- SPF in the morning — protecting expression zones from UV prevents worsening while the peptide works
Best For
- Expression lines
- Forehead lines
- Smile-line areas
- Targeted line-softening routines
- Peptide-focused users
How to Use
Apply a few drops morning and evening to expression-prone areas (forehead, between brows, around the eyes, smile lines) before heavier serums or creams.
Key Ingredients
Inhibits the SNARE protein complex that triggers muscle contractions involved in repetitive facial expressions. This mechanism theoretically reduces the formation of expression lines (forehead lines, crow's feet) with consistent use.
Ingredients to Note
May be a concern for some skin types. Tap to learn more.
Full Ingredient List
About This Product
The Ordinary Argireline Solution 10% delivers Acetyl Hexapeptide-8 (Argireline®) at a 10% concentration — one of the highest concentrations available in an OTC serum. Argireline is a synthetic hexapeptide designed to inhibit the SNARE complex mechanism partially involved in neuromuscular signal transmission, which may reduce the depth of repeated expression-related skin folds over time. It is particularly targeted at forehead lines, "11s," and expression-crease areas.