Matrixyl 10% + HA
A peptide-focused serum designed to target fine lines and improve the look of firmer, plumper skin.
A smart peptide serum for people who want a more line-focused age-support step without going straight to stronger retinoids or acids.
The combination of two Matrixyl systems at 10% total — a concentration higher than most dedicated peptide serums at 3–5x the price — makes this an exceptional value proposition. For people building a peptide-forward anti-aging routine, this delivers both matrikine systems in a single step.
Morning is ideal — it has no photosensitivity restriction, so the antioxidant and structural support pairs well with SPF. Can also be used evening, and many users apply it twice daily.
People who want a dedicated fine-line serum without retinol's downsides — sensitivity, peeling, and the need to avoid morning use. Also ideal for those who are pregnant, breastfeeding, or simply prefer a gentler approach to anti-aging.
If you expect retinol-speed results. Matrixyl peptides operate through a collagen synthesis pathway that takes 8–12 weeks to show visible improvement. If you give up at 3 weeks, you won't see what this formula can actually do.
One of the safest options to keep using during a skin flare-up. No active exfoliation, no photosensitivity, no harsh actives. It can stay in the routine while you scale back other steps.
- A lightweight SPF 30+ in the morning — the peptides and UV protection work synergistically for wrinkle prevention
- Multi-Peptide + HA Serum on alternating evenings for overlapping peptide coverage
- A ceramide-based moisturizer to lock in the serum and support the barrier
Best For
- Fine lines
- Early wrinkles
- Firmness
- Plumper-looking skin
- Peptide routines
- Gentle age-support
How to Use
Apply after cleansing and before moisturizer in the morning and/or evening. Can be used twice daily — there is no photosensitivity restriction.
Key Ingredients
Matrixyl 3000 sends matrikine signals to fibroblasts (the cells that produce collagen and elastin), stimulating the synthesis of key structural proteins. This reduces the visible depth of fine lines and wrinkles, improves firmness, and helps skin look plumper over consistent use.
Matrixyl Synthe'6 stimulates synthesis of six structural skin components: Collagen I, III, and IV, Fibronectin, Laminin-5 (now laminin-332), and Hyaluronic Acid. By expanding beyond what Matrixyl 3000 targets alone, it provides more comprehensive extracellular matrix support and deeper anti-aging coverage.
Draws water to the skin and helps lock it in, making skin appear plumper, smoother, and more hydrated.
Draws moisture to the skin, helps maintain hydration, and reinforces the skin barrier.
Ingredients to Note
May be a concern for some skin types. Tap to learn more.
Full Ingredient List
About This Product
The Ordinary Matrixyl 10% + HA is one of the highest-concentration Matrixyl formulas available at any price point. It combines two complementary matrikine peptide systems — Matrixyl 3000 (Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7) and Matrixyl Synthe'6 (Palmitoyl Tripeptide-38) — at a combined 10% concentration in a base of multi-weight hyaluronic acid. Matrixyl 3000 signals fibroblasts to produce collagen and elastin. Matrixyl Synthe'6 expands that target to six structural proteins including fibronectin, laminin-5, and hyaluronic acid. Combined at 10%, this formula delivers comprehensive collagen-synthesis support in a single lightweight serum without any of the downtime, photosensitivity, or irritation associated with retinoids.