The Ordinary GF 15% Solution serum for visible skin repair and wrinkles
The Ordinary

GF 15% Solution

Growth Factor SerumAll skin typesNormalDryCombinationOilyMature skin

An age-support serum with a 15% solution of growth factors designed to help minimize and repair visible skin damage while improving the look of aging skin.

Quick Verdict

A more advanced age-support serum for people focused on repair, visible skin damage, texture, and stronger anti-aging support.

ItGirlies Breakdown
Why People Buy This

Most growth factor serums sit behind very high price points at premium brands. The Ordinary delivering this at their typical price point brings a genuinely advanced anti-aging mechanism to routines that would otherwise never access it. For serious anti-aging users, this represents a significant opening.

Best Routine Slot

Evening after cleansing, before moisturizer, as the high-intensity treatment step. Or twice daily — follow with a well-formulated moisturizer to support the skin through the regeneration process.

Who Will Love This

Mature or prematurely aged skin that has already optimized SPF, barrier, and basic actives. People who want the next level beyond peptide serums — something operating at the cellular repair level rather than just collagen stimulation.

Most Likely to Backfire When…

If used at the same time as strong vitamin C formulas or direct acids (these can destabilize some growth factor types). Introduce alone and assess before layering aggressively.

If Your Skin Is Already Overwhelmed

Scale back to every other day and add a generous ceramide moisturizer after. Growth factors are generally well tolerated, but start slowly if your skin is currently stressed.

Pairs Well With
  • A ceramide-rich moisturizer immediately after — supports the skin through regeneration
  • SPF 30+ in the morning — UV protection is even more important when actively repairing skin
  • A niacinamide or barrier serum on non-GF evenings to balance the routine

Best For

  • Visible skin damage
  • Wrinkles
  • Texture
  • Signs of aging
  • Repair-focused age-support routines

How to Use

Apply after cleansing and before moisturizer in the morning and/or evening. Introduce gradually — start once daily and assess tolerance.

Key Ingredients

Growth Factors (15% Complex — SH-Oligopeptide-1, SH-Polypeptide-1, SH-Polypeptide-9)

Topical growth factors signal fibroblasts and keratinocytes to increase production of collagen, elastin, and other structural proteins — accelerating cell turnover, supporting wound healing pathways, and addressing visible signs of damage and aging. EGF (Epidermal Growth Factor / SH-Oligopeptide-1) is the most studied, with published data on visible skin repair and texture improvement.

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Hyaluronic Acid (Multi-Weight)

Draws water to the skin and helps lock it in, making skin appear plumper, smoother, and more hydrated.

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Glycerin

Draws moisture to the skin, helps maintain hydration, and reinforces the skin barrier.

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Ingredients to Note

Growth Factors (advanced formula — read precautions)

May be a concern for some skin types. Tap to learn more.

Phenoxyethanol (standard preservative)

May be a concern for some skin types. Tap to learn more.

About This Product

The Ordinary GF 15% Solution is the most advanced anti-aging serum in the current DECIEM range — a 15% concentration of biotechnologically derived growth factors that signal skin cells to repair, regenerate, and increase structural protein production. Growth factors (including EGF analogs and other oligopeptide growth factors) operate at the cellular communication level, directing fibroblasts and keratinocytes to produce collagen, elastin, and other structural proteins. This mechanism goes deeper than standard peptide serums — growth factors don't just stimulate collagen pathways, they signal comprehensive cellular repair. The result is a serum appropriate for visible skin damage, deeper wrinkles, and anyone who wants a more aggressive age-support approach than peptides alone.

Frequently Asked Questions

What does The Ordinary GF 15% Solution help with?
Visible skin damage, deeper wrinkles, texture, and signs of aging. Growth factors signal skin cells to produce collagen, elastin, and structural proteins — addressing aging at the cellular communication level rather than just the surface.
Is GF 15% Solution good for wrinkles?
Yes — it targets wrinkles through a repair-and-regeneration pathway that goes beyond what matrikine peptides alone can address. At 15% growth factors, this is one of the strongest OTC wrinkle-repair serums available.
Is this serum more advanced than a peptide serum?
Yes. Growth factors operate at the cellular signalling level — directing comprehensive repair and regeneration. Standard matrikine peptides like Matrixyl work through a single collagen-stimulation signal. GF 15% is the step up from Matrixyl or multi-peptide serums.
Who is most likely to like GF 15% Solution?
People with mature or sun-damaged skin focused on repair and visible wrinkle improvement who feel they've reached the ceiling of what peptide serums can do. Those building an advanced, comprehensive anti-aging routine where growth factors fill the highest-intensity step.