Beta Glucan
Also known as: Beta-Glucan, β-Glucan, Oat Beta Glucan, Sodium Carboxymethyl Beta-Glucan, Beta 1,3/1,6 Glucan
What It Is
A polysaccharide derived from oats, yeast, or other natural sources that functions simultaneously as a powerful skin-calming active, humectant, and immune-modulating support ingredient in cosmetic use.
What It Does
Beta glucan deeply hydrates through water-retaining (humectant) properties, signals keratinocytes and fibroblasts to reduce inflammatory cytokine activity, and modulates skin immune response — making it effective for calming visible redness and sensitivity while maintaining serious moisture retention. Research suggests some beta glucan forms also support collagen synthesis.
Best For
Benefits
- Powerful humectant: attracts and retains water comparable to hyaluronic acid
- Anti-inflammatory: reduces pro-inflammatory cytokine activity at the cellular level
- Immune-modulating: supports skin immune response and reduces reactivity
- Collagen-supportive: some research indicates fibroblast-stimulating properties
- Non-sensitizing: one of the most tolerated calming actives, suitable for reactive skin
When to Be Careful
- Less studied in cosmetics than HA despite similar or superior hydration mechanisms
- Often underdosed in premium-branded products — concentration matters
Beta glucan is arguably undervalued in Western skincare. The research on its hydration and anti-inflammatory properties rivals hyaluronic acid, and its immune-modulating function addresses a concern that HA doesn't touch. Its rise in The Ordinary's NMF formula brings it to a price point where its real performance can be tested widely.
Beta glucan is often seen as just a soothing botanical. It is a clinically active anti-inflammatory and humectant with a stronger research base than most "calming" ingredients. It's not just a bonus addition — in gel moisturizers, it's doing significant work.
Moisturizer step — morning and evening. In a gel texture, it sits comfortably under SPF.
Oily, combination, and sensitive skin wanting a gel moisturizer that doesn't just hydrate — it actively calms.
No known concerns — one of the most tolerated cosmetic ingredients.
No signs of overuse.